INGREDIENT GLOSSARY • Barrier Strengthener

Palmitoyl Oligopeptide-78


Palmitoyl Oligopeptide-78

Peptide that increases production of keratin, the key protein in stratum corneum barrier cells.

Type of Ingredient

Barrier Strengthener

Why we use it

Palmitoyl Oligopeptide-78 is a signaling peptide that tells keratinocytes to create more keratin. This family of proteins forms the backbone of our moisture barrier, keeping those skin cells strong, flexible, and resilient. When combined with Palmitoyl Heptapeptide-27, one study showed that after 28 days of daily use, epidermal thickness increased by 10% and transepidermal water loss (TEWL) decreased by 9%.

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